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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b4a93c5c981e5229c187b4eacaa508b4861a0987f8da3f7c5edb2522c2d9a4c2' 
  AND token = 'P0PGjfFGdsWa+DDWfEoIa1PEgFXZo8KpmOb68D2KySU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}