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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a33b9fa4f3f0e81bb4fafee45639e622ff0308a98d33134624e700415ab08a8' 
  AND token = 'HWOrcX02ddwkXlNFKkE+/MzvBbAnG4GoY8Ov2vwfD0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}