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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'daa400811a1d89afba35eafed4121114c7ec89a1fe783cf069b44a6bff338101' 
  AND token = 'jZxEKIay+dlaw0j9XJ6cFA6oUBOF/FD+wyZ3r6IrbFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}