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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10525e1745870b86d61757f928683f43d041b29cd798faf714ea6e742cd380d2' 
  AND token = 'fR2T0R7npC/BAd7WSB/mZ7olAmfh6NbDXtsZsQ1pjiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}