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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '20cb407156d7d3fba9232aa89fc4bd4e03674db6eb9852a54b17c5037431c2a0' 
  AND token = 'Hze/DasWsx5chYBWuocRChiRbmKCVSL+C2CBScAt4zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}