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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b16c403867c59959ae9d1c40a855c8ce7ea817af1b6279c65197e55669f79c4e' 
  AND token = 'j+0KU2fi20pfR/Rax0zl0kZM/vvVbUuHgbcDiJUpkHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}