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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22fbf2139838062d8457935afac528f12dd619bd544311383f00a24acbb294d8' 
  AND token = '2pxDJlczZytU+MyigG5vyWKX1VOdPyFjnEM8Erp7ytM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}