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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c3a46f0dd88eaa1b0a95803e87dc9300a870dfd4da13e024b1454ca665d753e2' 
  AND token = 'JEVeNR7qj6i8ShzV+xCwPb4hIcQSCzcbN7Vs+Dz2+0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}