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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '376342239ae39e4ebe51ec3a174f02ca404443b1c3f702b62f009be27b42a424' 
  AND token = 'Iumr2ZYELkQZfSjEZITd0Gbtye3A+YZU9Kj5ftjOA1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}