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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dcfe9ace0e222745635d265fb9250b09357132144e5daf9d523653cff6053a52' 
  AND token = 'vOTz6Nu5gZK+AFI315cF1d6Tva6MViqIpnbsBcAFMcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}