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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d86f9c73c5c3e34eaf666fc03d30265251426e29a3f03b47f4d210505e2c2fc' 
  AND token = 'b3Hc8yeXhsMRlwrxrRmsBhx6KkLrSxfMrhv61FmNiuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}