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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd5ea0651c5e7f7cfb3b85dcfc84c694ce25575b7b79a62e07956d1536f34e066' 
  AND token = 'EIREXvjufrN4fyrlOuk3YsK94P58fSxBbxNITyvADww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}