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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f36261296ae9ec4d4a63dc8965b59929fabdc42a780599b6b8e9e1fb98425fc5' 
  AND token = 'T1+xCw+MbkWRHwpo620aPhsjDNfRhQOqQHTLxfmv3hM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}