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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a22a04ca89f2857afe197bba816ee66ff4ea5e53ae04bf76f7bcebcaebcce4f' 
  AND token = '750fhZson03/y+TLKY2kYtKD5vLcVgTY39eMFhiJtm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}