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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7220110481c87253e5722048ce38ca975de47cd07bb7631547fdb84f65ed7b2b' 
  AND token = 'VfybNrVt7z+gsT0/YtDO7/odzSPyfFNK6B8B2hAr6JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}