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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4901b533c972c2369c3703449d0cb37bf528432745ca5de3eadd46938a1d2819' 
  AND token = 'qqTcgAOW7gd7hU8YlzM/MpTUexwyGz1l1lrIhfdhRgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}