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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '782cb9e22177295a61bb1bdeec5bc98ea47885014dd1ad48c23903eda61e2271' 
  AND token = 'zSKWk3Kyw96fblAejZwBXg9d8+avP/NAU81gv7rrPEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}