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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '41aedac0a3995812a40a7d8de5e57293f2cc9450d552e211a246683329f1624e' 
  AND token = 'ABEUa+cYwhYLd5APZVrGMCf9vFvEuHhliikENap6BcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}