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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '290043454fa47020dbe519c445f6b874847b202e47a75671059dda4070bce06f' 
  AND token = 'X1RD4UvL6kL8EqPhosYchU25yPwpockOPh1LAk4eHS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}