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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '01b0a34a1aebe817d78aa6bc45d4b19346f624e06b04e4b65501c347320b4452' 
  AND token = '7KnkTO1SCvRFx93VPjiqLEy6II113KPuK7vA1RQiHQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}