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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7a78d36abaa0ff4444ebca21c4727a6b4a5a10c5bd2a816806d3812a633bf0fd' 
  AND token = '3NxLVf8PXActLCAIKqtbUvdXf+yfjhWBYuTNbf/dtZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}