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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a83cde241b81e0c8b6c7c85be3b039a2ae4e4e864e209760565bddcd1af4f363' 
  AND token = 'QE60UPznaG/pcTBNge0YpkgcuJaMu0kKVQjYXwP3CC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}