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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '790edca71b316499fb9db3e2afb5f8b05afe4c3f5b3b501ee2021b7c91750331' 
  AND token = '8IQ7bud/keMeMV32qqRel4xJYPKBync6qkVhtl58Ykc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}