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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ae3ebcd3b8801bf45e05796787667688a6b3229f4c46321a180edd2c7aa476c8' 
  AND token = 'kxNWbhZ0SCB3RJg+By8P0gTgxrxRpb6Yq4hmRoPaZmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}