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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cd8ce15da97eec317d38417d5d8ad552302ed1c509e9ed9464ed8d288178e903' 
  AND token = 'fCGcUB2x+RwVBGJieioFFT7Z3O+ZPe0DpsBTtInf/Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}