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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cb48b8cf9b5cc8f04874d4b7f05df4f835360f4a181590dd85b68c449a6de153' 
  AND token = 'Bj09l0DUdd6eElvQmxM9zAM4rjZpfQ5uGDR7mfgEPHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}