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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cb968648caca33819a18e76ca1b9af590e052aec56e1d9eb4592ea5eadf2c181' 
  AND token = 'R4JgO1y+tvMZiCJOGiQq5zLdngsgggtT20mmT+7grDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}