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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e53fb322bf1892c483988615d5464da0911e4185cfce0aa449c74b12120a1000' 
  AND token = 'MDpyJ62oqL+MDUfSkH+f/lF/LP/rOIwLt02NR0d6F/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}