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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd01450d252576d009c7a6a537adeb5a5385ac7704ed33abf9146c643bbdd3315' 
  AND token = '0sHFEAEZE4z/J0bqM8q1tp2P1X3tr9au9DBDahdZsTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}