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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a72c181562495ea91999e71fda2942e39826e17d10cb4374e827bd948dac0f15' 
  AND token = 'GkNTZ8Jy00h9xbrJHxGMcvfsQZuaQrM7uQA3LA7B0zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}