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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ea4a7f65ae4bd3c0c5e09d9ed833769e4d867d81d40212b972db7561ab53a4c8' 
  AND token = 'ESTU/78qP5X2p3Am3C3qLFI8qeV5kiFaX7CT3XsMwlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}