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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2c7079a355add58581faf2812af030d530927771156894886937142d4ce5336' 
  AND token = 'F3brMXI8kBFY75kmjFEwNYaI9x4Vj1W5Gk+XciK0Vg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}