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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0b7f7e147b9bf3c4cdfdcefac0c429dbfcf6c92175d8df7c259cffe61a80dd75' 
  AND token = 'xy/RqUVGaG2z/rmr3U4+rB4jt8P4MVn/CCLDiAHBmiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}