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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25fe8c99deb4bcd54d7b6759c34be1bad62149cac8f1d6756ed29270f256c301' 
  AND token = 'TloygfeVqcn4ZeddkgHIdTKRqjxLui1lJYS3JvNbspU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}