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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aec5ef0d3200c33192a8d46ff9b81a192304b902fd3d14e9b809016e3507f877' 
  AND token = 'kCzvre+tPO3/2JE4rENq4TbpbsAerLTDSjleL5sYCcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}