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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '106fefffd35adbed7a7208d064ae2d93de512a9c7eed7841a630fbd8d85663d2' 
  AND token = 'lFKgA11tsTp6SiwOQq9dmZRlhVpxcARA5WyXzbPbreI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}