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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b49eef6b050a07faaebf9b826e94dcb5f71c186e0d9c32229e8e5d2bddf01a30' 
  AND token = 'FdHAxA1mY37YYNVu6MGB7gV115LDB895/NBvPvKu8ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}