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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1ccb5e6de79019c62f343a3b56593cdebe8757e495f7a635cd576f0df7aeb844' 
  AND token = 'E8T5j90BWpr3d4z7MgDte7BvFZ96l2sezo6ItBrwqB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}