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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'efc9f2c4e98ea06b4cb3251bfdbd582a4af3de8728d38c35a831fc717195a816' 
  AND token = '2eK4S3qhI8Hk+ZIxTD7TOTKsqNRSSTFCufTMdRyqqcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}