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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42fe2241938ff95a3b58e7da99eac99ad63dd22e0054e04b9eaa1f99b68266c1' 
  AND token = 'jy0ds7WbQbYwBVWlPu2f+zyqAWkaldT2jZBAusqCHYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}