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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd67e21e1e544650549de9c920bbf181e3eacd68058876a6609ebee2af3cdcc24' 
  AND token = 'dCMO0T537pYFEuSxu7B/ugFXBAJkBGjsEHYBjTKXY18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}