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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e4e6aa3004f560c0fa881a8423c54906d605a9cd12811a44aaf7046f0e9242c0' 
  AND token = 'OtRG9dsuBuSI2MSW6j8pDc2FOnjg4yN3NbJtTiHtvms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}