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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aacf10d1bd8495013f178d6c99db7a60bedface2970f8fe6b6a3aff2c594d305' 
  AND token = 'vUbkjo9Scxf0NEwSMVoXVZVTqqGn2OHT7VF8IfSnD84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}