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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0d59ebb0fcb1d6d980eaddaa591e3b671c5b9f1ca061d75456fc6de70e2c0880' 
  AND token = '9cBfLrLs+TBNhbQJEBER/Jq5kYBCo17MygCKZvZi/nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}