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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f03642d6795026a33301d6d0e12a83e3983e290f4b5ed2e48b00aeeaffcf0b65' 
  AND token = 'GX9D0hOH9Y4Sp1MoM49bx4fj1qVNcKKiTVGIEKodkxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}