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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'eaeeffb81c645dc6b8400ef5428a19a507a378eade7ca32b27797537e2714a1c' 
  AND token = 'iUlN8UcRGnnAuhNEz7rVJe+ZNqPBWF91tP3FWet+edk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}