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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '50ec4630bd463eed0d901f6efd33d3a3c8f8579073418e8af44ac623b10157a3' 
  AND token = 'vpp2IGx5miT1rYLRzNPX908oFYsIhRh6wKCY2LdRQlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}