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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '486e366b11a150a4b20a6a8ed74fb390a2a3eedc56ff0671a3b002971331bf3c' 
  AND token = '7Zu8RRWhRKrTWLncFEpIPmUAW+t9yrC9z7RAj7iInv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}