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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '777616a385818aa5dcd48a03a09d50f2d0d8638a27fdff731bb6cb092fa135c8' 
  AND token = 'PkUrTR8lVa8HUKwLz9aK19nZsbkSn2NvCVEZeW0DoKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}