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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'efa0df4c9f3fe94386ef29084f05f446b7020d5e92809fc14ca45ae34fb007bc' 
  AND token = 'JeSMn6T5kBfi7dR2uOmfZWi75UCqfeLqnCcJ91Lbm6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}